Hypoxia Inducible Factor (HIF) Activity Reporter Cell Line
US9995730B2 · kind B2 · utility
0Cited by
1References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 29, 2013 |
| Grant date | Jun 12, 2018 |
| Priority date | — |
| Expiry date | Jan 29, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/7038
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to the construction of a new hypoxia inducible factor (HIF) responsive reporter gene construct, the genetic constructs and vectors containing the same. Further, the present invention relates to a stable cell line comprising the HIF responsive reporter construct, as well as methods and uses of the inventive constructs and cell lines to identify modulators of HIF activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.