Peptide and peptidomimetic inhibitors

US9999650B2 · kind B2 · utility

Assignee

• RA PHARMACEUTICALS, INC. · US

Inventors

• Zhaolin Wang · Wellesley, US
• Ping Ye · Lexington, US
• Alonso Ricardo · Cambridge, US
• Kristopher Josephson · Wayland, US
• Paul Anderson · ᐙᔂᓂᐲ Waswanipi, CA
• Michelle Denise Hoarty · Billerica, US
• Zhong Ma · Lexington, US
• Nathan Ezekiel Nims · Winchester, US
• Eberhard Schneider · Wolfenbüttel, DE
• Gregor Schurmann · Hannover, DE
• Peter Wagner · Danville, US
• Douglas A. Treco · Arlington, US
• Hong Zheng · New York, US
• Daniel Elbaum · Newton, US
• Nicolas Cedric Boyer · Somerville, US

Key dates

• Filing date: Mar 15, 2017
• Grant date: Jun 19, 2018
• Expiry date: Mar 15, 2037

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides inhibitors and/or antagonists of plasma kallikrein. Also provided are methods of utilizing the inhibitors as therapeutics.