Fast and accurate proton therapy dose calculations

US9999788B2 · kind B2 · utility

Assignee

• International Business Machines Corporation · US

Inventors

• Anne Elizabeth Gattiker · Austin, US
• Damir A. Jamsek · Austin, US
• Sani R. Nassif · Austin, US
• Thomas H. Osiecki · Austin, US
• William E. Speight · Austin, US
• Chin Ngai Sze · Austin, US
• Min-Yu Tsai · Taipei, TW

Key dates

• Filing date: Jan 14, 2015
• Grant date: Jun 19, 2018
• Expiry date: Sep 19, 2036

Classification

• Technology area (CPC G): Physics
• CPC primary: G06F30/00
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Simulating particle beam interactions includes identifying a set of n functions F1, F2, . . . , Fn corresponding to a plurality of different physical aspects of a particle beam, performing simulations of each Fi using a full physics model, selecting for each Fi a distribution function fi that models relevant behavior and reducing computation of the full physics model for each Fi by replacing Fi with a distribution function fi. The computation reduction includes comparing a set of simulations wherein each fi replaces its respective Fi to determine if relevant behavior is accurately modeled and selecting one of fi or Fi for each n, for a Monte Carlo simulation based on a runtime and accuracy criteria.