Process for the production of 18F-2-deoxy-2-fluoro-D-glucose

USH74H · kind H · statutory invention registration

Assignee

• The United States of America as represented by the United States · US

Inventors

• Chyng-Yann Shiue · East Setauket, US
• Piero A. Salvadori · Pisa, IT
• Alfred P. Wolf · Setauket, US
• Joanna S. Fowler · Bellport, US
• Robert R. MacGregor · Sag Harbor, US

Key dates

• Grant date: Jun 3, 1986

Classification

• Technology area (CPC —): General

Abstract

Process for the production of 2-deoxy-2-fluoro-D-glucose and the corresponding .sup.18 F-compound by the reaction of acetyl hypofluorite or the corresponding .sup.18 F-compound with 3,4,6-tri-O-acetyl-D-glucal followed by hydrolysis. Process includes the production of the hypofluorite compound at ambient temperature.