Secondary phosphoric acid esters

USRE29202E · kind E · reissue

Assignee

• Leo Corporation

Inventors

• Knut Bertil Hogberg
• Hans Fex · Helsingborg, SE
• Bo Fredholm
• Torsten Perklev
• Sten Veige

Key dates

• Filing date: Aug 4, 1976
• Grant date: May 3, 1977
• Expiry date: Aug 4, 1996

Classification

• Technology area (CPC —): General

Abstract

Novel symmetrical secondary phosphoric acid esters having the general formula ##STR1## wherein the substituent R is positioned in meta or para position relative to the phosphoric acid ester group; processes for the preparation of said esters; and compositions containing said esters. The esters are i.a. useful as selective inhibitors of prostaglandins and compounds with prostaglandin activities. They also selectively antagonize the slow reacting substance (SRS).