Derivatives of 5-hydroxymethyl-3-substituted-2-oxazolidinones, process of preparation thereof and therapeutic application

USRE29607E · kind E · reissue

Assignee

• Delalande S.A. · FR

Inventors

• Claude P. Fauran · Paris, FR
• Guy M. Raynaud · Paris, FR
• Rene A. Oliver · Saint-Mandé, FR
• Colette A. Douzon · Paris, FR

Key dates

• Filing date: Jun 4, 1976
• Grant date: Apr 11, 1978
• Expiry date: Jun 4, 1996

Classification

• Technology area (CPC —): General

Abstract

Compounds of the formula ##STR1## in which R is H, .[.Cl, F, CH.sub.3 or CF.sub.3 .]. .Iadd.m-F, p-F, o-F, p-Cl, p-CH.sub.3, m-CH.sub.3 or m-CF.sub.3 .Iaddend.. The compounds are prepared by cyclizing with ethyl carbonate, a compound of the formula ##STR2## The compounds have anti-depressive, myorelaxing, tranquilizing, sedative, analgesic, anti-convulsive, anti-pyretic, anti-inflammatory and uricosuric activities.