Assay for myasthenia gravis
USRE30059E · kind E · reissue
1Cited by
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8Claims
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Key dates
| Filing date | Mar 20, 1978 |
| Grant date | Jul 31, 1979 |
| Priority date | — |
| Expiry date | Mar 20, 1998 |
Classification
- Technology area (CPC —)General
Abstract
A serum assay system for diagnosis of myasthenia gravis. The assay system includes a complex of acetylcholine receptor protein and a toxin labeled with a radioactive isotope. The complex is incubated with a serum sample from a patient. During incubation, antibodies engendered by myasthenia gravis bind to receptor sites in the complex. The resulting complex containing the antibodies is precipitated by addition of anti-immunoglobulin. Radioactivity in the resulting precipitate is measured and compared with a control.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.