Triaryl or diarylpyridyl methanes

USRE31467E · kind E · reissue

Assignee

• IMPERIAL CHEMICAL INDUSTRIES LIMITED · GB

Inventors

• Geraint Jones · Gloucester, GB
• David S. Thomson · Holmes Chapel, GB

Key dates

• Filing date: Mar 4, 1980
• Grant date: Dec 20, 1983
• Expiry date: Mar 4, 2000

Classification

• Technology area (CPC —): General

Abstract

Pharmaceutical compositions, containing a 4,4'-dihydroxy-3,3'-triphenylmethanedicarboxylic acid (or an oxidized derivative) as active ingredient, are described and are prepared conventionally in a form suitable for topical administration e.g. ointment. The compositions are useful for the treatment of inflammatory diseases and inflammatory conditions of the skin. Many of the active ingredients are novel compounds. A representative novel active ingredient is 4"-cyano-4,4'-dihydroxy-5,5'-dimethyl-3,3'-triphenylmethanedicarboxylic acid.