Derivatives of A-21978C cyclic peptides
USRE32311E · kind E · reissue
Assignee
Inventor
Key dates
| Filing date | Sep 25, 1985 |
| Grant date | Dec 16, 1986 |
| Priority date | — |
| Expiry date | Sep 25, 2005 |
Classification
- Technology area (CPC —)General
Abstract
A-21978C cyclic peptide derivatives of the formula ##STR1## wherein R is hydrogen, a specified aminoacyl or N-alkanoylaminoacyl group, 8-methyldecanoyl, 10-methyldodecanoyl, 10-methylundecanoyl, the specific C.sub.10 -alkanoyl group of A-21978C.sub.0 or the specific C.sub.12 -alkanoyl groups of A-21978C factors C.sub.4 and C.sub.5 or an amino-protecting group; and R.sup.1 is hydrogen, an amino-protecting group, or a specified aminoacyl or N-alkanoylaminoacyl group; provided that, when R is other than aminoacyl or N-alkanoylaminoacyl, R.sup.1 must be aminoacyl or N-alkanoylaminoacyl; and, when R.sup.1 is an amino-protecting group, R must be aminoacyl or N-alkanoylaminoacyl; and the salts thereof, are useful as antibacterial agents or as intermediates to antibacterial agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.