Patent · US Expired

Polycyclic heterocyclic compounds, a process for their preparation and their use in human and veterinary medicine

USRE33533E · kind E · reissue

4Cited by
2References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 24, 1990
Grant dateFeb 5, 1991
Priority date
Expiry dateApr 24, 2010

Classification

  • Technology area (CPC —)General

Abstract

A polycyclic heterocyclic compound has the formula ##STR1## wherein n is 1 or 2, R.sub.1 represents (i) lower alkyl, (ii)--CH.sub.2 OH or (iii) ##STR2## R.sub.2 represents (a) hydrogen, (b) ##STR3## or (c)--OR.sub.3, R.sub.3 represents hydrogen, C.sub.1 -C.sub.20 alkyl mono or polyhydroxyalkyl, aryl or aralkyl optionally substituted, the residue of a sugar or wherein p is 1, 2, or 3, and r' and r" represent hydrogen, lower alkyl, mono or polyhydroxalkyl, aryl optionally substituted, amino acid residue, aminated sugar residue, or together form a heterocycle, X represents oxygen, sulfur, SO, SO.sub.2 or --NR.sub.4, Y represents CR.sub.4 or a nitrogen atom and R.sub.4 represents hydrogen or lower alkyl. This polycyclic heterocyclic compound can be used in human and veterinary medicine and especially in the topical or systemic treatment of determatologic diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.