Method and composition for double receptor, specific binding assays
USRE34394E · kind E · reissue
11Cited by
24References
46Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 18, 1990 |
| Grant date | Sep 28, 1993 |
| Priority date | — |
| Expiry date | Dec 18, 2010 |
Classification
- Technology area (CPC —)General
Abstract
The performance of double receptor, specific binding assays is improved by use of a receptor complex having the structure EQU A.sub.BL (BL).sub.n A.sub.1 wherein BL is a binding ligand, A.sub.BL is a receptor specific for binding ligand, A.sub.1 is a receptor, BL is covalently bonded to A.sub.1 and A.sub.BL is reversibly bonded to BL. Generally A.sub.BL is absorbed onto an insoluble surface and A.sub.1 is an antibody to the substance being assayed. The complex has particular utility in coated tube and rechargeable radioimmunoassay systems.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.