Amines useful in producing pharmaceutically active CNS compounds

USRE35053E · kind E · reissue

Assignee

• The Upjohn Co. · US

Inventors

• John M. McCall · Kalamazoo, US
• E. Jon Jacobsen · Plainwell, US

Key dates

• Filing date: Oct 9, 1992
• Grant date: Oct 10, 1995
• Expiry date: Oct 9, 2012

Classification

• Technology area (CPC —): General

Abstract

Disclosed are .DELTA..sup.9(11) -steroids (VI) and amino substituted steroids (XI) which contain an amino group attached to the terminal carbon atom of the C.sub.17 -side chain, more particularly amino steroids (Ia and Ib), aromatic steroids (II), .DELTA..sup.16 -steroids (IIIa and IIIb), reduced A-ring steroids (IV), .DELTA..sup.17(20) -steroids (Va and Vb) and .DELTA..sup.9(11) -steroids (VI) which are useful as pharmaceutical agents for treating a number of conditions.