Rice dextrin oral rehydration solution

USRE36032E · kind E · reissue

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Michael C. Tao · Evansville, US
• Richard E. Litov · Evansville, US
• John R. Euber · Evansville, US
• Salim S. Akrabawi · Evansville, US
• J. Roberto Moran · Evansville, US

Key dates

• Filing date: Jun 3, 1993
• Grant date: Jan 5, 1999
• Expiry date: Jun 3, 2013

Classification

• Technology area (CPC —): General

Abstract

An improved oral rehydration solution comprising a mixture of rice dextrin and required electrolytes is provided. The functionality of the rice dextrin in oral rehydration solutions is superior to glucose in infants with chronic diarrhea.Iadd., .Iaddend.resulting in lower stool output and enhanced water retention .Iadd.during the initial six hours of therapy.Iaddend.. Rice dextrin also has a polymer profile which provides more readily available glucose than corn dextrin or rice flour. There is also provided a process for clarifying solutions of rice dextrin which involves a first filtration at 35.degree. C. and 50.degree. C. and a second filtration at temperatures above 80.degree. C. using filter aid and activated carbon.