HMG-CoA reductase inhibitors

USRE36520E · kind E · reissue

Assignee

• MERCK & CO., INC. · US

Inventors

• Robert L. Smith · Lansdale, US
• Wasyl Halczenko · Lansdale, US
• George D. Hartman · Lansdale, US
• Gerald E. Stokker · Gwynedd Valley, US
• Edward S. Inamine · Rahway, US
• Otto D. Hensens · Red Bank, US
• David Renwick Houck · Cary, US
• Ta J. Lee · Lansdale, US

Key dates

• Filing date: Nov 4, 1998
• Grant date: Jan 18, 2000
• Expiry date: Nov 4, 2018

Classification

• Technology area (CPC —): General

Abstract

Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors are useful as antihypercholesterolemic agents and are represented by the following general structural formula (II): ##STR1##