Patent · US Expired

Supplemented and unsupplemented tissue sealants, methods of their production and use

USRE39298E1 · kind E1 · reissue

16Cited by
97References
47Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 20, 2003
Grant dateSep 19, 2006
Priority date
Expiry dateJun 20, 2023

Classification

  • Technology area (CPC —)General

Abstract

This invention provides methods for the localized delivery of supplemented tissue sealants, wherein the supplemented tissue sealants comprise at least one composition which is selected from one or more antibodies, analgesics, anticoagulants, anti-inflammatory compounds, antimicrobial compositions, antiproliferatives, cytokines, cytotoxins, drugs, growth factors, interferons, hormones, lipids, demineralized bone or bone morphogenetic proteins, cartilage inducing factors, oligonucleotides polymers, polysaccharides, polypeptides, protease inhibitors, vasoconstrictors or vasodilators, vitamins, minerals, stabilizers and the like. Further provided are methods of using the site-specific supplemented tissue sealants, including preparation of a biomaterial.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.