Patent · US Expired

Substituted heterocycle fused gamma-carbolines

USRE39680E1 · kind E1 · reissue

97Cited by
22References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 16, 2006
Grant dateJun 5, 2007
Priority date
Expiry dateFeb 16, 2026

Classification

  • Technology area (CPC —)General

Abstract

The present invention is directed to certain novel compounds represented by structural Formula (I) or pharmaceutically acceptable salt forms thereof, wherein R1, R5, R6a, R6b, R7, R8, R9, X, b, k, m, and n, and the dashed lines are described herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are serotonin agonists and antagonists and are useful in the control or prevention of central nervous system disorders including obesity, anxiety, depression, psychosis, schizophrenia, sleep disorders, sexual disorders, migraine, conditions associated with cephalic pain, social phobias, and gastrointestinal disorders such as dysfunction of the gastrointestinal tract motility.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.