N-(2-aminophenyl)-4-[N-(pyridine-3-yl)-methoxycarbonyl-aminomethyl]-benzamide (MS-275) polymorph B

USRE45499E1 · kind E1 · reissue

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Matthias Schneider · Dossenheim, DE
• Michael Gottfried · Wuppertal, DE
• Jens Geisler · Berlin, DE
• Gabriele Winter · Lübbenau/Spreewald - Lubnjow/Błota, DE
• Joji Suzuki · Oomuta, JP
• Tomoyuki Ando · Chiba, JP
• Masaru Honjo · Yokohama, JP

Key dates

• Filing date: Mar 7, 2014
• Grant date: Apr 28, 2015
• Expiry date: Mar 7, 2034

Classification

• Technology area (CPC —): General

Abstract

The crystalline Polymorph B of N-(2-aminophenyl)-4-[N-(pyridine-3-yl)methoxy-carbonyaminomethyl]benzamide (MS-275) of formula Iis described, as well as the process for the production of said compound, and its use as a medicament for the treatment of selected diseases.