Oral dosage form comprising a therapeutic agent and an adverse-effect agent
USRE45822E1 · kind E1 · reissue
Assignee
Inventors
Key dates
| Filing date | Oct 28, 2013 |
| Grant date | Dec 22, 2015 |
| Priority date | — |
| Expiry date | Oct 28, 2033 |
Classification
- Technology area (CPC —)General
Abstract
The present invention provides an oral dosage form comprising a first composition and a second composition. The first composition comprises an effective amount of a therapeutic agent and the second composition comprises an effective amount of an adverse-effect agent. The adverse-effect agent is covered with a coating that is substantially insoluble in the gastrointestinal tract. In one embodiment, the adverse-effect agent is coated with an outer base-soluble layer and an inner acid-soluble layer. The therapeutic agent can be uncoated or can be coated with a coating having an outer acid-soluble layer and an inner base-soluble layer. The dosage form discourages administration of the therapeutic agent by other than oral administration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.