HDAC inhibitors and therapeutic methods using the same

USRE47009E1 · kind E1 · reissue

Assignees

• THE CHILDREN'S HOSPITAL OF PHILADELPHIA · US
• The Board of Trustees of the University of Illinois · US

Inventors

• Alan P. Kozikowski · Princeton, US
• Jay H. Kalin · Chicago, US
• Kyle Butler · Stanford, US
• Joel Bergman · Chicago, US
• Wayne W. Hancock · Philadelphia, US

Key dates

• Filing date: Jun 14, 2016
• Grant date: Aug 28, 2018
• Expiry date: Jun 14, 2036

Classification

• Technology area (CPC —): General

Abstract

Histone deacetylases inhibitors (HDACIs) and compositions containing the same are disclosed. Methods of treating diseases and conditions wherein inhibition of HDAC provides a benefit, like a cancer, a neurodegenerative disorder, a peripheral neuropathy, a neurological disease, traumatic brain injury, stroke, hypertension, malaria, an autoimmune disease, autism, autism spectrum disorders, and inflammation, also are disclosed.