Embolic compositions

USRE47121E1 · kind E1 · reissue

Assignee

• BioCure, Inc. · US

Inventors

• Dennis W. Goupil · Norcross, US
• Hassan Chaouk · Atlanta, US
• Troy Vernon Holland · Suwanee, US
• Bruktawit Asfaw · Mableton, US
• Stephen D. Goodrich · Woburn, US
• Lucas Latini · Norcross, US

Key dates

• Filing date: Jul 17, 2014
• Grant date: Nov 13, 2018
• Expiry date: Jul 17, 2034

Classification

• Technology area (CPC —): General

Abstract

Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as embolic agents to block and fill lumens and spaces. The embolic compositions can be used as liquid embolic agents and crosslinked in situ or as preformed embolic articles, such as microspheres.