EPHA2 receptor antagonist antibodies

USRE47123E1 · kind E1 · reissue

Assignee

• Sanofi · FR

Inventors

• Veronique Blanc · Paris, FR
• Claudia Fromond · Paris, FR
• Fabienne Parker · Saint-Maur-des-Fossés, FR
• Jiawen Han · Paris, FR
• Daniel Tavares · Natick, US
• Chonghui Zhang · Brookline, US
• Min Li · New Orleans, US
• Xiao-Mai Zhou · Danbury, US
• Michel Streuli · Brookline, US

Key dates

• Filing date: Aug 1, 2014
• Grant date: Nov 13, 2018
• Expiry date: Aug 1, 2034

Classification

• Technology area (CPC —): General

Abstract

Antagonistic antibodies that specifically bind to and inhibit Class A Eph receptors are provided. Also provided are cytotoxic conjugates, pharmaceutical compositions and kits comprising these antibodies.