Peptide epoxyketone immunoproteasome inhibitors
USRE47302E1 · kind E1 · reissue
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Key dates
| Filing date | Jun 23, 2017 |
| Grant date | Mar 19, 2019 |
| Priority date | — |
| Expiry date | Jun 23, 2037 |
Classification
- Technology area (CPC —)General
Abstract
Provided herein are tripeptide epoxy ketone protease inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula (X): and pharmaceutically acceptable salts and compositions including the same. The compounds and compositions provided herein may be used, for example, in the treatment of diseases including inflammation and neurodegenerative disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.