Recombinant production of mixtures of antibodies
USRE47770E1 · kind E1 · reissue
1Cited by
80References
23Claims
0Family size
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Key dates
| Filing date | May 18, 2016 |
| Grant date | Dec 17, 2019 |
| Priority date | — |
| Expiry date | May 18, 2036 |
Classification
- Technology area (CPC —)General
Abstract
Provided is methods for producing mixtures of antibodies from a single host cell clone, wherein, a nucleic acid sequence encoding a light chain and nucleic acid sequences encoding different heavy chains are expressed in a recombinant host cell. The recombinantly produced antibodies in the mixtures according to the invention suitably comprise identical light chains paired to different heavy chains capable of pairing to the light chain, thereby forming functional antigen-binding domains. Mixtures of the recombinantly produced antibodies are also provided by the invention. Such mixtures can be used in a variety of fields.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.