Methods of treating cancer with low density lipoprotein-related protein 6 (LRP6)—half life extender constructs
USRE47860E1 · kind E1 · reissue
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| Filing date | Nov 2, 2017 |
| Grant date | Feb 18, 2020 |
| Priority date | — |
| Expiry date | Nov 2, 2037 |
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- Technology area (CPC —)General
Abstract
The present invention relates to LRP6 constructs that bind to LRP6 receptor. The LRP6 constructs comprise at least one LRP6 binding moiety and a half-life extender molecule such that the LRP6 construct inhibit the Wnt signaling pathway without potentiation of the Wnt signal. The LRP6 constructs also have an increased half-life to provide more time for the therapeutic benefit.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.