Compositions and methods for inhibiting gene expression of hepatitis B virus

USRE48345E1 · kind E1 · reissue

Assignee

• Arrowhead Pharmaceuticals, Inc. · US

Inventors

• Daniel Chin · Foster City, US
• Jochen Deckert · Bayreuth, DE
• Markus Hossbach · Kulmbach, DE
• Matthias John · Hallstadt, DE

Key dates

• Filing date: Aug 19, 2016
• Grant date: Dec 8, 2020
• Expiry date: Aug 19, 2036

Classification

• Technology area (CPC —): General

Abstract

The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a Hepatitis B Virus gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by Hepatitis B Virus infection using said pharmaceutical composition; and methods for inhibiting the expression of a Hepatitis B Virus gene in a cell.