Patent · US Active

2-acylaminothiazole derivative or salt thereof

USRE49111E1 · kind E1 · reissue

2Cited by
2References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 23, 2020
Grant dateJun 21, 2022
Priority date
Expiry dateApr 23, 2040

Classification

  • Technology area (CPC —)General

Abstract

[Problem]To provide a compound which is useful as an active ingredient for a pharmaceutical composition for preventing or treating urine storage dysfunction, voiding dysfunction, lower urinary tract dysfunction, and the like.[Means for Solution]The present inventors have found that a thiazole derivative substituted with pyrazinylcarbonylamino at the 2-position is an excellent muscarinic M3 receptor-positive allosteric modulator and is expected as an agent for preventing or treating bladder/urinary tract diseases associated with bladder contractions via a muscarinic M3 receptor, thereby completing the present invention. 2-Acylaminothiazole derivative or a salt thereof of the present invention is expected as an agent for preventing or treating bladder/urinary tract diseases associated with bladder contractions via a muscarinic M3 receptor, for example voiding dysfunction such as underactive bladder.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.