Wnt pathway stimulation in reprogramming somatic cells with nuclear reprogramming factors
USRE49281E1 · kind E1 · reissue
Assignee
Inventors
Key dates
| Filing date | Dec 13, 2019 |
| Grant date | Nov 8, 2022 |
| Priority date | — |
| Expiry date | Dec 13, 2039 |
Classification
- Technology area (CPC —)General
Abstract
The invention provides compositions and methods of use in reprogramming somatic cells. Compositions and methods of the invention are of use, e.g., for generating or modulating (e.g., enhancing) generation of induced pluripotent stem cells by reprogramming somatic cells. The reprogrammed somatic cells are useful for a number of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a pluripotent state and/or enhances the speed and/or efficiency of reprogramming. Certain of the compositions and methods relate to modulating the Wnt pathway.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.