Inhibitors of TRPC6

USRE49699E1 · kind E1 · reissue

Assignees

• Boehringer Ingelheim International GmbH · DE
• Hydra Biosciences, LLC · US

Inventors

• Thierry Bouyssou · Mietingen, DE
• Dirk Gottschling · Mittelbiberach, DE
• Niklas Heine · Eberhardzell, DE
• Lana Louise Smith Keenan · Poughquag, US
• Michael Dennis Lowe · White Plains, US
• Hossein Razavi · Danbury, US
• Christopher Ronald Sarko · San Ramon, US
• Simon Surprenant · Boisbriand, CA
• Hidenori Takahashi · Lagrangeville, US
• Michael Robert Turner · Danbury, US
• Xinyuan Wu · Newton, US

Key dates

• Filing date: May 28, 2021
• Grant date: Oct 17, 2023
• Expiry date: May 28, 2041

Classification

• Technology area (CPC —): General

Abstract

The invention related to compounds of formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R2, A, Y and L are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.