Patent assignee · US · COMPANY

Macrogenics, Inc.

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128Patents
119Active
128Granted
57Portfolio score

Filing activity: May 29, 2003 → Aug 8, 2022 · 35 expiring within 5 years

Most-cited patents

PatentTitleAreaCited byStatus
US7355008B2 Identification and engineering of antibodies with variant Fc regions and methods of using same Physics 217 Expired
US7632497B2 Engineering Fc Antibody regions to confer effector function Chemistry; Metallurgy 146 Expired
US7960512B2 Identification and engineering of antibodies with variant Fc regions and methods of using same Chemistry; Metallurgy 122 Expired
US7425619B2 FcγRIIB specific antibodies and methods of use thereof Chemistry; Metallurgy 89 Expired
US8946387B2 FcγRIIB specific antibodies and methods of use thereof Chemistry; Metallurgy 79 Active
US8217147B2 Identification and engineering of antibodies with variant Fc regions and methods of using same Chemistry; Metallurgy 70 Active
US8003774B2 Identification and engineering of antibodies with variant Fc regions and methods of using same Physics 67 Active
US8193318B2 FcγRIIB specific antibodies and methods of use thereof Chemistry; Metallurgy 66 Active
US7521542B2 Humanized FcγRIIB-specific antibodies and methods of use thereof Chemistry; Metallurgy 64 Expired
US8192737B2 Identification and engineering of antibodies with variant Fc regions and methods of using same Physics 62 Active
US9822181B2 Bi-specific monovalent diabodies that are capable of binding CD123 and CD3, and uses thereof Chemistry; Metallurgy 57 Active
US7351803B2 CD16A binding proteins and use for the treatment of immune disorders Chemistry; Metallurgy 57 Expired
US8216574B2 Engineering Fc antibody regions to confer effector function Chemistry; Metallurgy 55 Active
US8187593B2 FcγRIIB specific antibodies and methods of use thereof Chemistry; Metallurgy 52 Active
US7700100B2 FcγRIIB fusion proteins and compositions thereof Chemistry; Metallurgy 49 Active
US8044180B2 FcγRIIB specific antibodies and methods of use thereof Chemistry; Metallurgy 44 Active
US8133982B2 FcγRIIB specific antibodies and methods of use thereof Chemistry; Metallurgy 43 Active
US7786270B2 Humanized FcγRIIB-specific antibodies and methods of use thereof Physics 43 Active
US7112439B2 Dual expression vector system for antibody expression in bacterial and mammalian cells Chemistry; Metallurgy 42 Expired
US9096877B2 Fc region-containing polypeptides that exhibit improved effector function due to alterations of the extent of fucosylation, and methods for their use Chemistry; Metallurgy 40 Active
US8216579B2 Humanized FcγRIIB-specific antibodies and methods of use thereof Physics 39 Active
US9587021B2 CD3-binding molecules capable of binding to human and non-human CD3 Emerging Cross-Sectional Technologies 27 Active
US8652466B2 Methods for the treatment of disease using immunoglobulins having Fc regions with altered affinities for FcγRactivating and FcγRinhibiting Chemistry; Metallurgy 26 Active
US8802091B2 Antibodies reactive with B7-H3 and uses thereof Chemistry; Metallurgy 26 Active
US9150656B2 Antibodies reactive with B7-H3, immunologically active fragments thereof and uses thereof Chemistry; Metallurgy 25 Active

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.