Inventor · Vancouver, BC, CA

Ian MacLachlan

51Patents
28h-index
34Co-inventors
88Inventor score

Filing activity: Feb 2, 1999 → Jan 12, 2024

Most-cited inventions

PatentTitleAreaCited byStatus
US8569256B2 Cationic lipids and methods for the delivery of therapeutic agents Chemistry; Metallurgy 331 Active
US8058069B2 Lipid formulations for nucleic acid delivery Chemistry; Metallurgy 283 Active
US7745651B2 Cationic lipids and methods of use Human Necessities 228 Active
US7799565B2 Lipid encapsulated interfering RNA Chemistry; Metallurgy 228 Expired
US7901708B2 Liposomal apparatus and manufacturing methods Human Necessities 216 Active
US7803397B2 Polyethyleneglycol-modified lipid compounds and uses thereof Chemistry; Metallurgy 190 Expired
US8329070B2 Liposomal apparatus and manufacturing method Human Necessities 141 Active
US9364435B2 Lipid formulations for nucleic acid delivery Chemistry; Metallurgy 141 Active
US8101741B2 Modified siRNA molecules and uses thereof Chemistry; Metallurgy 140 Active
US8188263B2 Modified siRNA molecules and uses thereof Chemistry; Metallurgy 132 Active
US8236943B2 Compositions and methods for silencing apolipoprotein B Emerging Cross-Sectional Technologies 128 Active
US9504651B2 Lipid compositions for nucleic acid delivery Human Necessities 122 Active
US7982027B2 Lipid encapsulated interfering RNA Human Necessities 115 Active
US8513403B2 Modified siRNA molecules and uses thereof Chemistry; Metallurgy 103 Active
US8999950B2 Compositions and methods for silencing aldehyde dehydrogenase Chemistry; Metallurgy 98 Active
US9018187B2 Cationic lipids and methods for the delivery of therapeutic agents Emerging Cross-Sectional Technologies 97 Active
US8283333B2 Lipid formulations for nucleic acid delivery Emerging Cross-Sectional Technologies 94 Active
US8936942B2 Polyethyleneglycol-modified lipid compounds and uses thereof Chemistry; Metallurgy 92 Active
US9074208B2 Modified siRNA molecules and uses thereof Chemistry; Metallurgy 88 Active
US9187748B2 Compositions and methods for silencing ebola virus gene expression Chemistry; Metallurgy 87 Active
US8822668B2 Lipid formulations for nucleic acid delivery Chemistry; Metallurgy 72 Active
US7838658B2 siRNA silencing of filovirus gene expression Chemistry; Metallurgy 66 Active
US9428751B2 Compositions and methods for silencing apolipoprotein C-III expression Chemistry; Metallurgy 64 Active
US9492386B2 Liposomal apparatus and manufacturing methods Human Necessities 60 Active
US7807815B2 Compositions comprising immunostimulatory siRNA molecules and DLinDMA or DLenDMA Chemistry; Metallurgy 58 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.