siRNA silencing of filovirus gene expression
US7838658B2 · kind B2 · utility
66Cited by
8References
45Claims
0Family size
Inventors
Key dates
| Filing date | Oct 20, 2006 |
| Grant date | Nov 23, 2010 |
| Priority date | — |
| Expiry date | Dec 4, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/14
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides siRNA molecules that target Filovirus gene expression and methods of using such siRNA molecules to silence Filovirus gene expression. The present invention also provides nucleic acid-lipid particles that target Filovirus gene expression comprising an siRNA that silences Filovirus gene expression, a cationic lipid, and a non-cationic lipid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.