Inventor · Del Mar, CA, US

Karl Y. Hostetler

71Patents
25h-index
22Co-inventors
88Inventor score

Filing activity: Aug 1, 1985 → Nov 10, 2021

Most-cited inventions

PatentTitleAreaCited byStatus
US5223263A Liponucleotide-containing liposomes Chemistry; Metallurgy 274 Expired
US5194654A Lipid derivatives of phosphonoacids for liposomal incorporation and method of use Chemistry; Metallurgy 256 Expired
US5411947A Method of converting a drug to an orally available form by covalently bonding a lipid to the drug Chemistry; Metallurgy 176 Expired
US5463092A Lipid derivatives of phosphonacids for liposomal incorporation and method of use Chemistry; Metallurgy 161 Expired
US5554728A Lipid conjugates of therapeutic peptides and protease inhibitors Chemistry; Metallurgy 130 Expired
US4692433A Method and composition for regulating serum calcium levels of mammals Human Necessities 90 Expired
US5484809A Prodrugs for oral administration containing taxol or substituted taxol covalently bound to a phospholipid Chemistry; Metallurgy 75 Expired
US6448392B1 Lipid derivatives of antiviral nucleosides: liposomal incorporation and method of use Chemistry; Metallurgy 75 Expired
US5654286A Nucleotides for topical treatment of psoriasis, and methods for using same Human Necessities 74 Expired
US6716825B2 Phosphonate compounds Chemistry; Metallurgy 63 Expired
US7749983B2 Metabolically stable alkoxyalkyl esters of antiviral or antiproliferative phosphonates, nucleoside phosphonates and nucleoside phosphates Chemistry; Metallurgy 63 Active
US7034014B2 Phosphonate compounds Chemistry; Metallurgy 49 Expired
US5696277A Antiviral prodrugs Chemistry; Metallurgy 47 Expired
US6599887B2 Methods of treating viral infections using antiviral liponucleotides Chemistry; Metallurgy 44 Expired
US7098197B2 Phosphonate compounds Chemistry; Metallurgy 40 Expired
US7094772B2 Phosphonate compounds Chemistry; Metallurgy 40 Expired
US6252060A Antiviral liponucleosides: treatment of hepatitis B Chemistry; Metallurgy 37 Expired
US7452898B2 Phosphonate compounds Chemistry; Metallurgy 34 Active
US7652001B2 Pharmacologically active agents containing esterified phosphonates and methods for use thereof Chemistry; Metallurgy 34 Active
US5580571A Nucleoside analogues Chemistry; Metallurgy 34 Expired
US5780617A Synthesis of liponucleotides Chemistry; Metallurgy 32 Expired
US7790703B2 Phosphonate compounds Chemistry; Metallurgy 32 Active
US6002029A Antiviral prodrugs Chemistry; Metallurgy 31 Expired
US7687480B2 Phosphonate compounds Chemistry; Metallurgy 27 Active
US5827831A Lipid nucleotide analog prodrugs for oral administration Chemistry; Metallurgy 27 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.