Inventor · Acton, MA, US

Klaus Charisse

41Patents
8h-index
36Co-inventors
71Inventor score

Filing activity: Sep 22, 2010 → May 3, 2023

Most-cited inventions

PatentTitleAreaCited byStatus
US9796974B2 Modified RNAi agents Chemistry; Metallurgy 85 Active
US9399775B2 RNAi agents, compositions and methods of use thereof for treating transthyretin (TTR) associated diseases Chemistry; Metallurgy 29 Active
US9783806B2 TMPRSS6 iRNA compositions and methods of use thereof Chemistry; Metallurgy 13 Active
US9127274B2 Serpinc1 iRNA compositions and methods of use thereof Chemistry; Metallurgy 12 Active
US11504391B1 Modified RNA agents with reduced off-target effect Chemistry; Metallurgy 12 Active
US9249415B2 Complement component C5 iRNA compositions and methods of use thereof Chemistry; Metallurgy 11 Active
US9574192B2 Serapina1 iRNA compositions and methods of use thereof Chemistry; Metallurgy 10 Active
US10668170B2 Modified RNAi agents Chemistry; Metallurgy 8 Active
US10238749B2 Angiotensinogen (AGT) iRNA compositions and methods of use thereof Chemistry; Metallurgy 8 Active
US10570391B2 RNAi agents, compositions and methods of use thereof for treating transthyretin (TTR) associated diseases Chemistry; Metallurgy 8 Active
US10995336B2 Serpina1 iRNA compositions and methods of use thereof Chemistry; Metallurgy 6 Active
US9701963B2 Complement component C5 iRNA compositions and methods of use thereof Chemistry; Metallurgy 6 Active
US10030244B2 Serpina1 iRNA compositions and methods of use thereof Chemistry; Metallurgy 6 Active
US9850488B2 Complement component C5 iRNA compositions and methods of use thereof Chemistry; Metallurgy 5 Active
US9376680B2 Serpinc1 iRNA compositions and methods of use thereof Chemistry; Metallurgy 5 Active
US10913950B2 TMPRSS6 iRNA compositions and methods of use thereof Chemistry; Metallurgy 4 Active
US10125369B2 PCSK9 iRNA compositions and methods of use thereof Chemistry; Metallurgy 4 Active
US9068184B2 Compositions and methods for inhibition of expression of protein C (PROC) genes Chemistry; Metallurgy 3 Active
US11406716B2 Modified RNAi agents Chemistry; Metallurgy 3 Active
US11597932B2 Chirally-enriched double-stranded RNA agents Chemistry; Metallurgy 3 Active
US10920223B2 Serpina1 iRNA compositions and methods of use thereof Chemistry; Metallurgy 2 Active
US9970006B2 Compositions and methods for inhibition of expression of apolipoprotein C-III (APOC3) genes Chemistry; Metallurgy 2 Active
US10988768B2 TMPRSS6 iRNA compositions and methods of use thereof Chemistry; Metallurgy 2 Active
US9315813B2 Compositions and methods for inhibition of expression of apolipoprotein C-III (APOC3) genes Chemistry; Metallurgy 2 Active
US10683504B2 Serpina1 iRNA compositions and methods of use thereof Chemistry; Metallurgy 2 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.