Patent · US Active

Serpina1 iRNA compositions and methods of use thereof

US10920223B2 · kind B2 · utility

2Cited by
5References
45Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 14, 2018
Grant dateFeb 16, 2021
Priority date
Expiry dateJun 14, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2330/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the Serpina1 gene, and methods of using such RNAi agents to inhibit expression of Serpina1 and methods of treating subjects having a Serpina1 associated disease, such as a liver disorder.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.