Mark S. Chee
182Patents
73h-index
85Co-inventors
93Inventor score
Filing activity: Oct 21, 1994 → Mar 7, 2025
Most-cited inventions
| Patent | Title | Area | Cited by | Status |
|---|---|---|---|---|
| US6355431B1 | Detection of nucleic acid amplification reactions using bead arrays | Emerging Cross-Sectional Technologies | 837 | Expired |
| US6040138A | Expression monitoring by hybridization to high density oligonucleotide arrays | Physics | 707 | Expired |
| US5837832A | Arrays of nucleic acid probes on biological chips | Chemistry; Metallurgy | 698 | Expired |
| US9085798B2 | Nucleic acid constructs and methods of use | Chemistry; Metallurgy | 451 | Active |
| US6429027B1 | Composite arrays utilizing microspheres | Emerging Cross-Sectional Technologies | 451 | Expired |
| US6013440A | Nucleic acid affinity columns | Chemistry; Metallurgy | 439 | Expired |
| US6890741B2 | Multiplexed detection of analytes | Emerging Cross-Sectional Technologies | 390 | Expired |
| US6344316B1 | Nucleic acid analysis techniques | Physics | 381 | Expired |
| US6544732B1 | Encoding and decoding of array sensors utilizing nanocrystals | Emerging Cross-Sectional Technologies | 370 | Expired |
| US6620584B1 | Combinatorial decoding of random nucleic acid arrays | Chemistry; Metallurgy | 361 | Expired |
| US9371598B2 | Spatially encoded biological assays | Physics | 347 | Active |
| US6156501A | Arrays of modified nucleic acid probes and methods of use | Chemistry; Metallurgy | 332 | Expired |
| US7582420B2 | Multiplex nucleic acid reactions | Emerging Cross-Sectional Technologies | 310 | Expired |
| US7060431B2 | Method of making and decoding of array sensors with microspheres | Emerging Cross-Sectional Technologies | 270 | Expired |
| US9868979B2 | Spatially encoded biological assays using a microfluidic device | Performing Operations; Transporting | 263 | Active |
| US6942968B1 | Array compositions for improved signal detection | Chemistry; Metallurgy | 262 | Expired |
| US9879313B2 | Methods and systems for determining spatial patterns of biological targets in a sample | Performing Operations; Transporting | 256 | Active |
| US7033754B2 | Decoding of array sensors with microspheres | Emerging Cross-Sectional Technologies | 252 | Expired |
| US8460865B2 | Multiplex decoding of array sensors with microspheres | Emerging Cross-Sectional Technologies | 225 | Active |
| US6309823A | Arrays of nucleic acid probes for analyzing biotransformation genes and methods of using the same | Chemistry; Metallurgy | 218 | Expired |
| US5795716A | Computer-aided visualization and analysis system for sequence evaluation | Physics | 208 | Expired |
| US7955794B2 | Multiplex nucleic acid reactions | Chemistry; Metallurgy | 207 | Expired |
| US8003354B2 | Multiplex nucleic acid reactions | Chemistry; Metallurgy | 206 | Active |
| US6468744B1 | Analysis of genetic polymorphisms and gene copy number | Chemistry; Metallurgy | 204 | Expired |
| US7226734B2 | Multiplex decoding of array sensors with microspheres | Emerging Cross-Sectional Technologies | 201 | Expired |
Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.