Inventor · Portola Valley, CA, US

Robert L. Coffman

31Patents
7h-index
37Co-inventors
69Inventor score

Filing activity: Oct 29, 1975 → Oct 11, 2023

Most-cited inventions

PatentTitleAreaCited byStatus
US5096704A Method of treating eosinophilia Emerging Cross-Sectional Technologies 29 Expired
US8940310B2 Methods of treatment using TLR7 and/or TLR9 inhibitors Emerging Cross-Sectional Technologies 13 Active
US5601815A IL-4 and IL-10 to downregulate delayed-type hypersensitivity and cytokine expresion by T-cells Human Necessities 11 Expired
US8759305B2 Methods and compositions for inhibition of innate immune responses and autoimmunity Chemistry; Metallurgy 9 Active
US4121983A Metal production Chemistry; Metallurgy 9 Expired
US9993495B2 Intrapulmonary administration of polynucleotide toll-like receptor 9 agonists for treating cancer of the lung Human Necessities 7 Active
US8815817B2 Long term disease modification using immunostimulatory oligonucleotides Human Necessities 7 Active
US9950064B2 Branched and linear chimeric compounds, polynucleotides, uses and methods for preparation thereof Chemistry; Metallurgy 5 Active
US8252757B2 Long term disease modification using immunostimulatory oligonucleotides Chemistry; Metallurgy 5 Active
US6207155A Method of eosinophil depletion with antibody to CCR 3 receptor Human Necessities 5 Expired
US10722591B2 Cleavable conjugates of TLR7/8 agonist compounds, methods for preparation, and uses thereof Chemistry; Metallurgy 5 Active
US8962579B2 Methods and compositions for inhibition of immune responses and autoimmunity Chemistry; Metallurgy 4 Active
US10751412B2 Combination of a PD-1 antagonist and CPG-C type oligonucleotide for treating cancer Chemistry; Metallurgy 3 Active
US3974080A Silicone hydraulic fluids Chemistry; Metallurgy 3 Expired
US10111899B2 Intrapulmonary administration of polynucleotide toll-like receptor 9 agonists for treating cancer of the lung Human Necessities 2 Active
US11370794B2 Toll-like receptor antagonist compounds and methods of use Chemistry; Metallurgy 2 Active
US9063123B2 Transgenic mice expressing human toll-like receptor 8 Chemistry; Metallurgy 1 Active
US11827641B2 Toll-like receptor antagonist compounds and methods of use Chemistry; Metallurgy 1 Active
US11124510B2 Alkyl chain modified imidazoquinoline TLR7/8 agonist compounds and uses thereof Human Necessities 1 Active
US9347064B2 Methods of treatment using TLR7 and/or TLR9 inhibitors Emerging Cross-Sectional Technologies 1 Active
US4259161A Process for producing aluminum and electrodes for bipolar cell Chemistry; Metallurgy 1 Expired
US5676940A Method of reducing immunoglobulin E responses Human Necessities 1 Expired
US12296002B2 Immunogenic composition against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Chemistry; Metallurgy 0 Active
US12378255B2 Toll-like receptor antagonist compounds and methods of use Chemistry; Metallurgy 0 Active
US9476053B2 Methods and compositions for inhibition of immune responses and autoimmunity Chemistry; Metallurgy 0 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.