Patent · US Active

Benzimidazole derivatives as bromodomain inhibitors

US10017501B2 · kind B2 · utility

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1References
15Claims
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Assignee

Inventors

Key dates

Filing dateAug 17, 2016
Grant dateJul 10, 2018
Priority date
Expiry dateAug 17, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This application relates to chemical compounds which may act as inhibitors of, or which may otherwise modulate the activity of, a bromodomain-containing protein, including bromodomain-containing protein 4 (BRD4), and to compositions and formulations containing such compounds, and methods of using and making such compounds. Compounds include compounds of Formula (I) wherein R1a, R1b, R2a, R2b, R3, R4a, R4b, and R5 are described herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.