Patent assignee · US · COMPANY

Gilead Sciences, Inc.

🏢 View company profile →
923Patents
736Active
923Granted
61Portfolio score

Filing activity: Sep 23, 1988 → May 16, 2025 · 117 expiring within 5 years

Most-cited patents

PatentTitleAreaCited byStatus
US5484908A Oligonucleotides containing 5-propynyl pyrimidines Chemistry; Metallurgy 624 Expired
US5502177A Pyrimidine derivatives for labeled binding partners Emerging Cross-Sectional Technologies 594 Expired
US5594121A Enhanced triple-helix and double-helix formation with oligomers containing modified purines Chemistry; Metallurgy 587 Expired
US5466786A 2'modified nucleoside and nucleotide compounds Chemistry; Metallurgy 573 Expired
US5264564A Oligonucleotide analogs with novel linkages Chemistry; Metallurgy 569 Expired
US5264562A Oligonucleotide analogs with novel linkages Chemistry; Metallurgy 560 Expired
US5596086A Modified internucleoside linkages having one nitrogen and two carbon atoms Chemistry; Metallurgy 543 Expired
US5830653A Methods of using oligomers containing modified pyrimidines Chemistry; Metallurgy 523 Expired
US5633360A Oligonucleotide analogs capable of passive cell membrane permeation Chemistry; Metallurgy 503 Expired
US5645985A Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines Emerging Cross-Sectional Technologies 502 Expired
US5399676A Oligonucleotides with inverted polarity Emerging Cross-Sectional Technologies 490 Expired
US5434257A Binding compentent oligomers containing unsaturated 3',5' and 2',5' linkages Chemistry; Metallurgy 490 Expired
US6005096A Pyrimidine derivatives Emerging Cross-Sectional Technologies 455 Expired
US5256775A Exonuclease-resistant oligonucleotides Chemistry; Metallurgy 435 Expired
US5763588A Pyrimidine derivatives for labeled binding partners Emerging Cross-Sectional Technologies 426 Expired
US5214136A Anthraquinone-derivatives oligonucleotides Chemistry; Metallurgy 281 Expired
US5792608A Nuclease stable and binding competent oligomers and methods for their use Chemistry; Metallurgy 259 Expired
US5792847A 2' Modified Oligonucleotides Chemistry; Metallurgy 254 Expired
US5672697A Nucleoside 5'-methylene phosphonates Chemistry; Metallurgy 251 Expired
US5486603A Oligonucleotide having enhanced binding affinity Chemistry; Metallurgy 250 Expired
US5582981A Method for identifying an oligonucleotide aptamer specific for a target Physics 241 Expired
US5527899A Oligonucleotides with inverted polarity Emerging Cross-Sectional Technologies 239 Expired
US5194599A Hydrogen phosphonodithioate compositions Chemistry; Metallurgy 226 Expired
US5646269A Method for oligonucleotide analog synthesis Chemistry; Metallurgy 225 Expired
US5565555A Nucleoside hydrogen phosphonodithioate diesters and activated phosphonodithioate analogues Chemistry; Metallurgy 217 Expired

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.