Piperidine isoxazole and isothiazole orexin receptor antagonists
US10017504B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 27, 2015 |
| Grant date | Jul 10, 2018 |
| Priority date | — |
| Expiry date | Oct 27, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to piperidine isoxazole and isothiazole orexin compounds which are antagonists of orexin receptors. Such compounds are of the general structural formula I: wherein the variables are defined herein. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.