Patent assignee · US · COMPANY

Merck Sharp & Dohme LLC

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2,399Patents
1,991Active
2,399Granted
62Portfolio score

Filing activity: Dec 23, 1980 → Sep 19, 2024 · 660 expiring within 5 years

Most-cited patents

PatentTitleAreaCited byStatus
US5514718A Heterocyclic compounds, processes for their preparation and pharmaceutical compositions containing them Chemistry; Metallurgy 531 Expired
US8168757B2 PD-1 binding proteins Chemistry; Metallurgy 319 Active
US8900587B2 Antibodies to human programmed death receptor PD-1 Physics 128 Active
USD780909S1 Autoinjector pen General 100 Active
US7879815B2 Nucleoside aryl phosphoramidates for the treatment of RNA-dependent RNA viral infection Human Necessities 100 Active
US7833992B2 Conjugates and compositions for cellular delivery Emerging Cross-Sectional Technologies 97 Active
US5880132A Tachykinin antagonist and an opioid analgesic effective at treating pain or nociception Human Necessities 93 Expired
US8188234B2 1D05 PCSK9 antagonists Chemistry; Metallurgy 87 Active
USD774641S1 Auto injector General 84 Active
US8273866B2 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA) Chemistry; Metallurgy 81 Active
US8188233B2 1B20 PCSK9 antagonists Chemistry; Metallurgy 81 Active
US8648185B2 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Emerging Cross-Sectional Technologies 80 Active
US8618277B2 RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Chemistry; Metallurgy 79 Active
US6172077A Spiro-azacyclic derivatives and their use as therapeutic agents Human Necessities 74 Expired
US6214846A Substituted 3-(benzylamino)piperidine derivatives and their use as therapeutic agents Chemistry; Metallurgy 74 Expired
US8148349B2 Nucleoside cyclic phosphoramidates for the treatment of RNA-dependent RNA viral infection Human Necessities 72 Active
US5298520A Triazole containing indole derivatives Chemistry; Metallurgy 72 Expired
US8071568B2 Nucleoside aryl phosphoramidates for the treatment of RNA-dependent RNA viral infection Chemistry; Metallurgy 71 Active
USD857192S1 Autoinjector device General 70 Active
US6479480B1 Phenylindole derivatives as 5-ht2a receptor ligands Chemistry; Metallurgy 69 Expired
US5106853A Oxadiazole and its salts, their use in treating dementia Human Necessities 67 Expired
US7775056B2 Intelligent refrigerator for storing pharmaceutical product containers Mechanical Engineering; Lighting; Heating 67 Active
US5556969A Benzodiazepine derivatives Chemistry; Metallurgy 63 Expired
US5346906A Substituted pyridines, their preparation, formulations and use in dementia Chemistry; Metallurgy 62 Expired
USD793547S1 Autoinjector pen General 60 Active

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.