5-aminotetrahydroquinoline-2-carboxylic acids and their use

US10053428B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Michael Hahn · Langenfeld, DE
• Markus Follmann
• Eva-Maria Becker · Wuppertal, DE
• Johannes-Peter Stasch · Wuppertal, DE
• Joerg Keldenich · Wuppertal, DE
• Martina Delbeck · Essen, DE
• Hanna Tinel · Wuppertal, DE
• Frank Wunder · Wuppertal, DE
• Joachim Mittendorf · Wuppertal, DE
• Ildiko Terebesi · Berlin, DE
• Dieter Lang · Velbert, DE
• René Martin · Leipzig, DE
• Walter Hubsch · Wuppertal, DE

Key dates

• Filing date: May 19, 2017
• Grant date: Aug 21, 2018
• Expiry date: May 19, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel 5-amino-5,6,7,8-tetrahydroquinoline-2-carboxylic acids, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular and cardiopulmonary disorders.