Methods for treating, diagnosing, and monitoring lupus
US10053734B2 · kind B2 · utility
1Cited by
15References
22Claims
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Key dates
| Filing date | Feb 10, 2016 |
| Grant date | Aug 21, 2018 |
| Priority date | — |
| Expiry date | Feb 10, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of identifying, diagnosing, and prognosing lupus, including certain subphenotypes of lupus, are provided, as well as methods of treating lupus, including certain subpopulations of patients. The methods provided are based on a set of alleles associated with systemic lupus erythematosus (SLE) risk loci including BLK, TNIP1, PRDM1, JAZF1, UHRF1BP1, IL10, IFIH1, CFB, CEC16A, IL12B and SH2B3 that contribute to SLE risk. Also provided are methods for identifying effective lupus therapeutic agents and predicting responsiveness to lupus therapeutic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.