Patent assignee · US · COMPANY

Genentech, Inc.

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3,353Patents
1,584Active
3,353Granted
56Portfolio score

Filing activity: Jul 5, 1979 → Dec 20, 2024 · 442 expiring within 5 years

Most-cited patents

PatentTitleAreaCited byStatus
US4816567A Recombinant immunoglobin preparations Emerging Cross-Sectional Technologies 4,524 Expired
US5821337A Immunoglobulin variants Chemistry; Metallurgy 1,271 Expired
US6737056B1 Polypeptide variants with altered effector function Chemistry; Metallurgy 1,238 Expired
US6054297A Humanized antibodies and methods for making them Chemistry; Metallurgy 956 Expired
US6194551A Polypeptide variants Chemistry; Metallurgy 940 Expired
US6407213B1 Method for making humanized antibodies Chemistry; Metallurgy 885 Expired
US5731168A Method for making heteromultimeric polypeptides Chemistry; Metallurgy 852 Expired
US5116964A Hybrid immunoglobulins Chemistry; Metallurgy 799 Expired
US5869046A Altered polypeptides with increased half-life Chemistry; Metallurgy 717 Expired
US5750373A Enrichment method for variant proteins having altered binding properties, M13 phagemids, and growth hormone variants Emerging Cross-Sectional Technologies 617 Expired
US6171586A Antibody formulation Chemistry; Metallurgy 611 Expired
US6331415A Methods of producing immunoglobulins, vectors and transformed host cells for use therein Emerging Cross-Sectional Technologies 578 Expired
US5641870A Low pH hydrophobic interaction chromatography for antibody purification Emerging Cross-Sectional Technologies 564 Expired
US6267958A Protein formulation Emerging Cross-Sectional Technologies 541 Expired
US5821047A Monovalent phage display Emerging Cross-Sectional Technologies 534 Expired
US5175273A Nucleic acid intercalating agents Chemistry; Metallurgy 495 Expired
US6528624B1 Polypeptide variants Chemistry; Metallurgy 493 Expired
US5122469A Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins Chemistry; Metallurgy 472 Expired
US5648237A Expression of functional antibody fragments Emerging Cross-Sectional Technologies 468 Expired
US6121022A Altered polypeptides with increased half-life Chemistry; Metallurgy 454 Expired
US7521541B2 Cysteine engineered antibodies and conjugates Chemistry; Metallurgy 445 Expired
US5677171A Monoclonal antibodies directed to the HER2 receptor Chemistry; Metallurgy 422 Expired
US5514097A Self administered injection pen apparatus and method Human Necessities 386 Expired
US8217149B2 Anti-PD-L1 antibodies, compositions and articles of manufacture Emerging Cross-Sectional Technologies 385 Active
US6538124B1 Polypeptide variants Chemistry; Metallurgy 381 Expired

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.