Compounds and methods for the treatment of malaria

US10059711B2 · kind B2 · utility

Assignee

• The Broad Institute, Inc. · US

Inventors

• Eamon Comer · Cambridge, US
• Nobutaka Kato · Cambridge, US
• Christina Scherer · Seattle, US
• Jessica Marine Aurore BASTIEN · Cambridge, US
• Jeremy R. DUVALL · Topsfield, US
• Timothy A. Lewis · Marlborough, US
• Morgane Sayes · Cambridge, US
• Matthew Leighty · Cambridge, US
• Jun Pu · Cambridge, US
• Jennifer Beaudoin · Holden, US
• Bertrand Braibant · Cambridge, US
• Benito Munoz · San Diego, US

Key dates

• Filing date: Nov 11, 2014
• Grant date: Aug 28, 2018
• Expiry date: Nov 11, 2034

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of malaria.