Compounds for treatment of pain

US10072018B2 · kind B2 · utility

Assignee

• BIOPHARMA WORKS · US

Inventors

• Robert A. Volkmann · Mystic, US
• Anthony Marfat · Mystic, US
• Peter Cornelius · Framingham, US
• Panayiotis Zagouras · Old Saybrook, US
• Fredrick Raymond Nelson · Groton, US
• Anton Fliri · Stonington, US

Key dates

• Filing date: Apr 16, 2014
• Grant date: Sep 11, 2018
• Expiry date: Apr 16, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The aspects of the disclosed embodiments are directed to novel compounds, specifically, quaternary ammonium derivatives of tertiary amine containing opioid drug compounds such as hydrocodone, hydromorphone and oxycodone, formulations containing said. compounds or pharmaceutically acceptable salts thereof, which are capable of providing controlled release of the opioid drug upon administration to a patient in order to treat pain.