Camelid single-domain antibody directed against phosphorylated tau proteins and methods for producing conjugates thereof
US10087245B2 · kind B2 · utility
4Cited by
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25Claims
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Key dates
| Filing date | Jan 28, 2015 |
| Grant date | Oct 2, 2018 |
| Priority date | — |
| Expiry date | Jan 28, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2821
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to variable domains of a camelid heavy-chain antibodies directed against a phosphorylated tau protein and conjugates thereof. The present invention also relates to the use of these domains or conjugates for treating or diagnosing disorders mediated by neurofibrillary tangles, neuropil threads or dystrophic neurites, such as tauopathies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.