Compositions and methods for detection of drug resistant Mycobacterium tuberculosis
US10087490B2 · kind B2 · utility
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Key dates
| Filing date | Dec 18, 2014 |
| Grant date | Oct 2, 2018 |
| Priority date | — |
| Expiry date | Feb 6, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for the rapid detection of the presence or absence of Mycobacterium tuberculosis (MTB) resistant to rifampicin (MTB-RIF) and/or MTB resistant to isoniazid (MTB-INH) in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers, probes targeting the genes for rpoB, inhA, and katG, along with kits are provided that are designed for the detection of MTB-RIF and/or MTB-INH.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.