Compositions for detecting complement factor H (CFH) and complement factor I (CFI) polymorphisms
US10093978B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Aug 11, 2014 |
| Grant date | Oct 9, 2018 |
| Priority date | — |
| Expiry date | Oct 6, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods and compositions for treating various degenerative diseases (e.g., AMD) with a factor D inhibitor (e.g., anti-factor D antibody or antigen-binding fragment thereof). Also provided are methods of selecting or identifying patients for treatment with a factor D inhibitor. Methods include the use of prognostic and/or predictive biomarkers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.