Patent · US Active

Fused heterocyclic compounds as CaM kinase inhibitors

US10100058B2 · kind B2 · utility

0Cited by
1References
33Claims
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Assignee

Inventors

Key dates

Filing dateNov 29, 2017
Grant dateOct 16, 2018
Priority date
Expiry dateNov 29, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure relates to compounds that are CaM Kinase inhibitors and to their use in the treatment of various disease states, including atrial fibrillation and myocardial infarction. In particular embodiments, the general structure of the compounds is given by Formula I: wherein R1, R2, R3, R4, R5, R6, R9 and R10 are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.