Method for differentiation of pluripotent stem cells into multi-competent renal precursors
US10138468B2 · kind B2 · utility
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Key dates
| Filing date | Jan 29, 2016 |
| Grant date | Nov 27, 2018 |
| Priority date | — |
| Expiry date | Jan 29, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/45
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This application relates to a method for differentiating pluripotent stem cells (PSCs) into multi-competent renal precursor cells expressing Six2. These renal precursor cells are able to differentiate into fully functional and fully differentiated podocytes. Moreover this application relates to a method for differentiating human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) into defined renal precursor cells expressing Six2 and podocytes based on linked steps of chemically defined medium inductions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.